On an ordinary day in the basement of a modern-day superheroes' mansion, Cyanide Lou (played by Joe Budden), and A.P.R.I.M.A.L. (9th Wonder), are working on their latest project, "Primal Poisoning," when a distraught Professor Ecks (Lupe Fiasco), informs them that they have just lost funding for their long-awaited project. The original financial backer and confidant of the House of M, Aultmon Capital Management Group, has fallen due to the current financial woes of the world and is barely able to monetarily maintain its own operations. Distant member of the House of M, S. Dot MCrary (Silkk the Shocker), whose involvement in Milwaukee's criminal underworld leads him to an alternate sponsorship from the city's biggest rap-recording/drug overlord crime boss, Dutch Wacktagon (Treach). Not knowing the background of this fiendish crook-turned-Milwaukee rap mogul, Cyanide Lou and A.P.R.I.M.A.L. agree to receive his questionable funding.
After completing their classic work, the album is submitted to Dutch for final approval and distribution. He approves the project and "Primal Poisoning," is ready to be pressed and released to the awaiting hip-hop world.
At the albums listening party, the venue's DJ plays the "traditional" artists that Dutch is accustomed to signing, and as the party builds to a peak, Lou & P.R.I.M.A.L. are introduced to the crowd. Lou & P.R.I.M.A.L. set the mood perfect with their well-spoken introduction to, "Primal Poisoning." If not like turning the pillow to the cool side only to find a smelly batch of discomfort, the speakers blare out piercing synth beats, with A.P.R.I.M.A.L.-sounding rhymes, but certainly not P.R.I.M.A.L.'s rhymes verbatim. Thinking this is a mistake, Lou attempts to apologize to the crowd only to be escorted off the stage by Dutch's henchmen who cynically explain that this was a set-up to bring Milwaukee's sacred hip-hop scene into the grasp of the Wacktagon empire.
"No one will ever go for this shit!," A.P.R.I.M.A.L. responds. "Oh really?," Dutch asks while glaring over the crowd. "It would seem as if it's working already." Lou and P.R.I.MA.L. look to the crowd to see their peers, with whom they've shared distaste for this type of wackness, getting crunk to the music and reciting the cliche hook...
"GET LOW HO/ TO THE FLO HO/
NOW BOUNCE THAT ASS TO THE BEAT/
NOW BOUNCE THAT ASS TO THE BEAT/"
The song becomes an instant hit and is heard on the radio all across the Midwest, then garners national attention. Now it is up to the two men who still have hip-hop's best interests in mind, to save it...

Cast, in order of appearance:

Cyanide Lou (Joe Budden)



A.P.R.I.M.A.L. (9th Wonder)



Professor Ecks (Lupe Fiasco)



S. Dot McCrary (Silkk the Shocker)



Dutch Wacktagon (Treach)